Teen stress may raise risk of postpartum depression in adults

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Teen stress may raise risk of postpartum depression in adults

Source:
Johns Hopkins Medicine
Summary:
A research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.

In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth. The researchers say this corresponds to the equivalent hormonal changes in postpartum women who were exposed to adverse early life experiences -- suggesting that early life stress may underlie a pathophysiological exacerbation of postpartum depression (PPD).

The team's findings, first published online Apr. 11, 2024, in Nature Mental Health, also suggest that current drug treatments for PPD in people may, in some cases, be less effective at targeting the relevant chemical imbalances in the brain, and that alternative methods may be more beneficial.

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